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We have existed since , when our founder Diane Ifode felt there was a gap missing in a market for a laid back social night that didn't consist of raving, screw faces and people vomiting. So Lela's Lounge was born an alternative social events company.
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At the start of we decided it was time for newness and so we evolved into The Kickback. The Kickback is an alternative experience for young professionals wanting to enhance their social life. Although currently based in London we have our eyes set on the world, there are no limits to what we can do. Microscope image shows an immunological synapse.
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This, however, could not be proved for the other molecules. Dustin to simulate the formation of synapses using computer models. In these models, they simulated different conditions and influencing factors and were able to demonstrate that the different molecules exert an influence on each other in terms of their arrangement although they do not interact directly. Computer simulation of an immunological synapse with its characteristic ring-shaped structure. The antigen receptors are small and are repelled by the large adhesion molecules.
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They organise themselves in small clusters which are transported by actin in the direction of the centre of the synapse. The large adhesion molecules accumulate around them in an outer ring. The ring pattern is thus a result of mechanical forces in the cell membrane which sorts the molecules in the synapse according to their size. From a medical point of view, these results are of particular significance for the area of treatment of defective T-cell activity.
In this way, activation of T-cells may be induced or slowed down, which could be used for improved management of acute or chronic infections, improved results from vaccination or prevention of autoimmune diseases.
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Anastasios Siokis, Philippe A. Robert, Philippos Demetriou, Michael L.
Cell Reports, , DOI: HZI researchers have investigated the formation of immunological synapses over which immune cells exchange information The immune system protects the human body against pathogens thus keeping it healthy. Involved Groups Systems Immunology.
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